Understanding the genetics of antipsychotic treatment response
Marcus Munafo looks at a Chinese genome-wide association study that claims to have identified some of the genes associated with response to antipsychotic treatment. The post Understanding the genetics...
View ArticleThe genetics of depression (and anxiety!)
Thalia Eley shares her thoughts on a recent Nature genome-wide association study of depression phenotypes in the UK Biobank, which uses different definitions of depression to provide more tractable...
View ArticleDepression and anxiety: two sides of the same coin? #TransDX2018
Ava Schulz reviews a paper by Mansell and McEvoy which looks at psychopathology in a heterogenous clinical sample of anxiety and depression. The post Depression and anxiety: two sides of the same coin?...
View ArticleWhat can genetics tell us about the link between cannabis and schizophrenia?...
Suzi Gage summarises a recent GWAS of lifetime cannabis use, which reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia. Interesting new evidence...
View ArticleImproving antidepressant outcomes: what works for whom and why?
Thalia Eley and Gerome Breen explore a new systematic meta-review of predictors of antidepressant treatment outcome in depression, which looks at clinical and demographic variables, but also biomarkers...
View ArticleGenetics of depression: understanding risk and improving treatment
Douglas Levinson on a genome-wide meta-analysis of depression in 807,553 individuals, which identifies 102 independent variants relating to the genetics of depression. The post Genetics of depression:...
View ArticleGenetic predictors of depression trajectories in adolescence
Megan Skelton explores a study that uses polygenic scores in the context of longitudinal developmental data, to characterise developmental trajectories and the role of neuropsychiatric genetic risk...
View ArticleNew genes implicated in Alzheimer’s disease #LetsTalkMentalHealthII
Byron Creese writes a #LetsTalkMentalHealthII blog about a recent genome-wide meta-analysis which identifies new loci and functional pathways influencing Alzheimer's disease risk. The post New genes...
View ArticleWho gets bullied? Using genetic information to identify individual...
Lucy Bowes explores a multi-polygenic score approach to identifying individual vulnerabilities associated with the risk of bullying, which suggests that depression, ADHD, risk taking, BMI and...
View ArticleWhat causes Autistic Spectrum Disorder?
Ben Janaway explores a recent review in JAMA Psychiatry on the emerging clinical neuroscience of Autism Spectrum Disorder. The post What causes Autistic Spectrum Disorder? appeared first on National...
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